Program
Download the short program 
here;
and the complete program (including abstracts) here.
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| Monday | Tuesday | Wednesday |
Monday, 11 September
| 10:00 – 11:00 | Registration |
| Lecture hall 2 |
Opening |
| 11:00 – 11:10 | Welcome to Friedrich Schiller University (FSU) Jena Walter Rosenthal, President FSU |
| 11:10 – 11:20 | Welcome to Jena and Thuringia Wolfgang Tiefensee, State Minister of Economy, Science and the Digital Society of Thuringia |
| 11:20 – 11:25 | Leibniz Institute on Aging – Fritz Lipmann Institute FLI Daniela Barthel, Administrative Director |
| 11:25 – 11:30 | GSCN Annual Conference 2017 Ulrich Martin, President GSCN |
| 11:30 – 12:15 |
Keynote lecture K1 – Stem cells in silence, action and cancer Elaine Fuchs, Howard Hughes Medical Institute, Rockefeller University, New York, USA Chair: Ana Martin-Villalba |
| 12:15 – 13:00 | Keynote lecture K2 – Age-related stem cell dysfunction: causes and consequences Heinrich Jasper, Buck Institute, Novato, USA Chair: Hartmut Geiger |
| 13:00 – 14:30 |
Lunch break / Industry exhibition |
| Lecture hall 2 |
Scientific working group session I (Chairs: Micha Drukker/Thomas Braun) |
| 14:30 – 14:50 |
T01 – Control of mammalian neurogenesis Federico Calegari, Center for Regenerative Therapies / TU Dresden |
| 14:50 – 15:35 |
Pluripotency and reprogramming |
| 14:50 – 15:05 | T02 – FACT is a reprogramming barrier in C. elegans and human cells Baris Tursun, Max Delbrück Center for Molecular Medicine (MDC), Berlin |
| 15:05 – 15:20 |
T03 – A novel molecular mechanism of cell-fusion mediated reprogramming Karthik Arumugam, Centre for Genomic Regulation (CRG), Barcelona, Spain |
| 15:20 – 15:35 | T04 – Directing cell fates with artificially evolved transcription factors Ralf Jauch, Guangzhou Institutes of Biomedicine and Health, China |
| 15:35 – 16:20 |
Somatic stem cells and development |
| 15:35 – 15:50 | T05 – Single-cell RNA sequencing reveals aging-induced quiescence in neural stem cells of the subventricular zone Georgios Kalamakis, German Cancer Research Center (DKFZ), Heidelberg |
| 15:50 – 16:05 |
T06 – Vitamin A in stem cell aging Simon Schwörer, Leibniz Institute on Aging/Fritz Lipmann Institute (FLI), Jena |
| 16:05 – 16:20 |
T07/P103 – Regulation of epidermal stem cells by flightless I protein during wound repair Nanxing Yang, University of South Australia, Adelaide |
| 16:30 – 16:45 | Scientific working group discussions I |
| Lecture hall 2 |
Pluripotency and reprogramming |
| Lecture hall 5 |
Somatic stem cells and development |
| 16:30 – 18:00 |
Coffee break / Industry exhibition |
| Lecture hall 3 |
GSCN General membership meeting |
| 17:00 – 18:00 |
GSCN membership meeting |
| 18:00 – 20:00 | Poster session I: P001 – P068 P001 – P028: Stem cells in regenerative therapies P029 – P068: Stem cells in disease modeling and drug development Even numbers: please present your poster from 18:00 – 19:00 Odd numbers: 19:00 – 20:00 Posters can be mounted on 11 September 13h and should be removed until 12 September 13:30h. |
| 20:00 – 21:30 | Informal GSCN get together for all participants with dinner buffet at the foyer |
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Tuesday, 12 September
| Lecture hall 2 |
Scientific working group session II (Chairs: Andreas Trumpp/Claudia Waskow) | |
| 09:00 – 09:20 | T08 – Learning hematopoietic stem cell dynamics from fate mapping Thomas Höfer, German Cancer Research Center (DKFZ), Heidelberg |
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| 09:20 – 09:50 | Hematopoietic stem cells |
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| 09:20 – 09:35 | T09 – Human haematopoietic stem cell differentiation follows a continuous Waddington-like landscape Simon Haas, German Cancer Research Center (DKFZ) / HI-STEM, Heidelberg |
|
| 09:35 – 09:50 | T10 – Paraoxonase-2 and its effects on hematopoietic stem cell proliferation and differentiation Lisa Spiecker, University Medical Center of the Johannes Gutenberg-University Mainz |
|
| 09:50 – 10:20 | Computational stem cell biology |
|
| 09:50 – 10:05 | T11 – A computational systems biology approach to identify niche determinants of stem cell identity Srikanth Ravichandran, University of Luxembourg |
|
| 10:05 – 10:20 | T12 – Adult neural stem cells increase the rate of asymmetric divisions during aging Lisa Bast, TU Munich, Helmholtz Zentrum Munich |
|
| 10:20 – 10:50 | Stem cells in disease: cancer stem cells |
|
| 10:20 – 10:35 | T13 – Myeloid leukemia stem cells depend on phospholipase C gamma 1 (Plcg1) signaling Tina Schnöder, University Hospital & Leibniz Institute on Aging, Jena |
|
| 10:35 – 10:50 | T14/P069 – C/EBPβ-LIP regulates the let-7/Lin28 circuit to control cellular metabolism Tobias Ackermann, European Research Institute for the Biology of Ageing (ERIBA), Groningen, The Netherlands |
|
| 11:00 – 11:15 |
Scientific working group discussions II |
|
| Lecture hall 2 |
Hematopoietic stem cells |
|
| Lecture hall 3 |
Computational stem cell biology |
|
| Lecture hall 5 |
Stem cells in disease: cancer stem cells |
|
| 11:00 – 11:30 |
Coffee break /Industry exhibition |
|
| 11:30 – 13:00 |
Industry session: “Technologies from GSCN industry partners” |
|
| Lecture hall 2 |
Main supporter (Chair: Frank Edenhofer) |
|
| 11:30 – 12:00 | C1 – Tissue engineering of primary human in vitro models – influence of mechanical and biochemical stimulation on tissue functionality Antje Appelt-Menzel, University Hospital & Fraunhofer IGB Würzburg, representing PeproTech GmbH |
|
| 12:00 – 12:30 | C2 – Evolving media systems for modern stem cell applications David Kuninger, Thermo Fisher Scientific |
|
| 12:30 – 13:00 | C3 – Current challenges in stem cell production for regenerative medicine and drug development Christof Knocke, Eppendorf AG |
|
| Lecture hall 3 |
Supporter (Chair: Benedikt Berninger) |
|
| 11:30 – 12:00 | C4 – Novel technologies for the cultivation and quality control of iPSCs and their derivatives Sebastian Knöbel, Miltenyi Biotec GmbH |
|
| 12:00 – 12:30 | C5 – A novel maintenance medium extends the life-span and enables long term applications for both human primary hepatocytes and human pluripotent stem cell derived hepatocytes in conventional 2D cultures
Barbara Küppers-Munther, Takara Bio Europe, SAS |
|
| 12:30 – 13:00 | C6 – Novel serum-free, xeno-free vitronectin-based culture system for hPSC Suzanne Badoux, Biological Industries (BI), Ltd. |
|
| Lecture hall 5 |
Supporter (Chair: Insa Schröder) |
|
| 11:30 – 12:00 | C7 – Avoid irrelevant, non-reproducible data – the neglected variable: physiologic oxygen Paul Michaels, BioSpherix, Ltd. |
|
| 12:00 – 12:30 | C8 – Systems and solutions for culture and scale up of human pluripotent stem cells Florent Bornes, Corning B.V. Life Sciences |
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| 12:30 – 13:00 | C9 – Highly efficient single-cell human pluripotent stem cell cloning and robust cardiomyocyte differentiation Katharina Debowski, STEMCELL Technologies GmbH |
|
| 13:00 – 14:30 | Lunch break / Industry exhibition / Poster viewing | |
| 13:15 – 14:15 | Meet-the-expert tables(limited to 10 registered participants each) |
|
| Room 121 Room 122 Room 131 |
Thomas Höfer, DKFZ (Bioinformatic tools in stem cell research) Thomas Braun, MPI (Stem cell approaches in heart and lung development) Claudia Waskow, TU Dresden (Hematopoietic stem cells) |
|
| Lecture hall 2 |
Presidential Symposium Chair: Ulrich Martin |
|
| 14:30 – 15:15 |
PS1 – Cerebral organoids: modelling human brain development and tumorigenesis in stem cell derived 3D culture Jürgen Knoblich, IMBA, Vienna, Austria |
|
| 15:15 – 15:45 | Female Scientist Award 2017 PS2 – Unraveling the cellular and molecular basis of limb regeneration Elly Tanaka, Research Institute of Molecular Pathology (IMP), Vienna, Austria |
|
| 15:45 – 16:15 |
Young Investigator Award 2017 PS3 – DNA methylation and demethylation dynamics in stem cells Francesco Neri, Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), Jena |
|
| 16:15 – 16:45 | Publication of the Year 2017 Award PS4 – Multilineage communication regulates human liver bud development from pluripotency J. Gray Camp, Max Planck Institute for Evolutionary Anthropology, Leipzig |
|
| 16:45 – 17:00 |
Wine & cheese / Industry exhibition |
|
| 17:00 – 19:00 | Poster session II: P069 – P142 P069 – P076: Stem cells in diseases: cancer stem cells P077 – P084: Computational stem cell biology and systems biology P085 – P103: Somatic stem cells and development P104 – P124: Pluripotency and reprograming P125 – P142: Hematopoietic stem cells Even numbers: please present your poster from 17:00 – 18:00 Odd numbers: 18:00 – 19:00 Posters can be mounted on 12 September 14h and should be removed until 13 September 14:30h. |
|
| 19:30 – 01:00 |
GSCN Networking evening for all participants with dinner buffet and DJ at the Volksbad (within walking distance to the FSU) |
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Wednesday, 13 September
| |
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| Lecture hall 2 |
Scientific working group session III (Chairs: Bert Klebl/Richard Schäfer) | |
| 09:00 – 09:20 | T15 – Stem cell based assays as the next generation phenotypic drug screens? Bert Klebl, Lead Discovery Center (LDC), Dortmund |
|
| 09:20 – 10:05 | Stem cells in regenerative therapies | |
| 09:20 – 09:35 | T16 – Human iPSC-derived phagocytes as a cellular therapeutic to treat bacterial infections Nico Lachmann, REBIRTH / Hannover Medical School (MHH) |
|
| 09:35 – 09:50 | T17 – HMGB1 accelerates regeneration of multiple tissues by transitioning stem cells to G(Alert) Ana Isabel Espirito Santo, University of Oxford, UK |
|
| 09:50 – 10:05 | T18 – Metabolic targeting by mesenchymal stem cells in a mouse model of diet-induced NASH Bruno Christ, University Hospital Leipzig |
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| 10:05 – 10:50 | Stem cells in disease modeling and drug development |
|
| 10:05 – 10:20 | T19/P055A – Genetically encoded calcium indicators for drug screening in human engineered heart tissues Umber Saleem, University Medical Center Hamburg-Eppendorf (UKE) |
|
| 10:20 – 10:35 | T20/P065 – Establishment of murine 3D bronchoalveolar lung organoids from adult somatic stem cells for organ development and disease modeling Ana Ivonne Vazquez Armendariz, Universities Giessen & Marburg Lung Center (UGMLC) |
|
| 10:35 – 10:50 | T21 – A xenotransplantation approach using human pluripotent stem cell-derived pancreatic organoids Meike Hohwieler, University Medical Center Ulm |
|
| 11:00 – 11:15 | Scientific working group discussions III | |
| Lecture hall 2 | Stem cells in regenerative therapies | |
| Lecture hall 5 | Stem cells in disease modeling and drug development | |
| 11:00 – 11:30 |
Coffee break / Industry exhibition | |
| 11:30 – 13:00 | Concurrent strategic working group session | |
| Lecture hall 2 |
Career development Chairs: Hartmut Geiger, Insa Schröder |
|
| 11:30 – 12:15 | S1 – Options and opportunities for scientists in science communication Tobias Maier, Nationales Institut für Wissenschaftskommunikation gGmbH |
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| 12:15 – 13:00 | S2 – Tips and tools for efficient science communication in the public and private sector Stefanie Seltmann, Pfizer Deutschland GmbH, Berlin |
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| Lecture hall 3 | Technologies in stem cell research Chairs: Andreas Bosio, Michael Cross |
|
| 11:30 – 12:10 | S3 – Reconstructing human neurogenesis using single-cell transcriptomics Barbara Treutlein, Max Planck Institute for Evolutionary Anthropology, Leipzig |
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| 12:10 – 12:50 | S4 – Multimodal single cell genomics Sascha Sauer, Max Delbrück Center Berlin |
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| 12:50 – 13:00 | Panel discussion on Technologies with Barbara Treutlein & Sascha Sauer; Moderation: Andreas Bosio & Michael Cross | |
| Lecture hall 5 | Clinical trials and regulatory affairs Chairs: Zoltan Ivics, Ralf Sanzenbacher,Torsten Tonn |
|
| 11:30 – 12:00 | S6 – Development of (stem) cell-based medicinal products: Regulatory aspects Ralf Sanzenbacher, Paul Ehrlich Institute, Langen |
|
| 12:00 – 12:30 | S7 – Development of (stem) cell-based medicinal products: turning research into GMP Martin Hildebrandt, TUMCells Interdisciplinary Center for Cellular Therapies, TUM Muinch |
|
| 12:30 – 13:00 | S8 – Development of (stem) cell-based medicinal products: Clinical Considerations for Cell-Based Therapies Mohamed Abou-El-Enein, Berlin-Brandenburg Center for Regenerative Therapies (BCRT) |
|
| 13:00 – 14:30 |
Lunch break / Industry exhibition / Poster viewing |
|
| 13:15 – 14:15 | Meet-the-expert tables (limited to 10 registered participants each) | |
| Room 121 Room 122 Room 131 |
Ralf Sanzenbacher, PEI, Langen (ATMPs and GMP) Andreas Bosio, Miltenyi, Bergisch Gladbach (Technologies and private sector) Bert Klebl, LDC, Dortmund (Disease modeling and translation) |
|
| Lecture hall 2 | Joined session with FLI Chair: Claudia Waskow |
|
| 14:30 – 15:15 |
Keynote lecture K3 – Deconstructing pancreatic development and disease with human pluripotent stem cells Maike Sander, University of San Diego, California, USA Chair: Julia v. Maltzahn |
|
| 15:15 – 15:35 | FLI01 – Maintenance of Jak-inhibitor treated MPN depends on cold shock protein Ybx1 Florian Heidel, Universitätsklinikum Jena |
|
| 15:35 – 15:55 |
P096 – Meaningful modeling of cortical development and microcephaly in rosettes and organoids derived by combined pathway inhibition Yechiel Elkabetz, Max Planck Institute for Molecular Genetics, Berlin |
|
| 15:55 – 16:15 |
P117 – EOMES is a context?dependent master regulator of cardiac induction in human ES cells Boris Greber, Max Planck Institute for Molecular Biomedicine, Münster |
|
| 16:15 – 16:35 | FLI02 – Functional relevance of Klotho for maintenance and regeneration of skeletal muscle Julia v. Maltzahn, Leibniz Institute on Aging/Fritz Lipmann Institute (FLI), Jena |
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| Lecture hall 2 | Closing ceremony | |
| 16:35 – 17:00 | Poster award ceremony and announcement of industry quiz winners Daniel Besser, GSCN |
|
| End of GSCN conference 2017 |
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| Announcement: | ||
| 18:30 – 21:00 | GSCN Public outreach event with panelists (in German) Moderne Zelltherapien – Stammzellen bei Alterung, Krebserkrankungen & Organoiden Podiumsdiskussion zur aktuellen Forschung mit Wissenschaftlern und Ärzten Volksbad Knebelstraße 10 07743 Jena |
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| Grundlagenforschung an Stammzellen bietet wichtige Erkenntnisse für die Entwicklung moderner Zelltherapien. Heute erhalten Sie Antworten auf Ihre Fragen:
• Wie laufen Alternsprozesse in Stammzellen ab? • Warum nehmen Krankheiten mit steigendem Alter zu? • Wie können Krankheitsverläufe z.B. bei Blutkrebs durch Stammzelltherapie verändert werden? • Welche Forschungsmöglichkeiten bieten Organoide aus Stammzellen? • Wie ist der Stand der Forschung? • Welche Aussichten zeichnen sich für die Klinik und die Anwendung ab? Wissenschaftler und Ärzte aus Jena, Wien, Heidelberg und Dresden stellen den aktuellen Stand der Grundlagenforschung und den möglichen klinischen Einsatz moderner Zelltherapien vor. Kurze Filme veranschaulichen ihre Arbeit. Anschließend diskutieren die Experten Einsatzmöglichkeiten von Stammzellen bei Alternsprozessen und Erkrankungen und beantworten Fragen aus dem Publikum: Prof. Dr. Florian Heidel, Universitätsklinikum Jena & Leibniz-Institut für Alternsforschung – Fritz-Lipmann-Institut Prof. Dr. Jürgen Knoblich, Institut für Molekulare Biotechnologie, Wien Prof. Dr. Andreas Trumpp, Deutsche Krebsforschungszentrum, Heidelberg Prof. Dr. Claudia Waskow, TU Dresden Moderation: Dr. Stefanie Seltmann |
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Thursday, 14 SeptemberAs a satellite event to the conference the non-PI meeting will be held on 14 September. In the registration process Students and Postdocs have the possibility to apply to participate in the non-PI meeting until 19 June. It offers the unique opportunity to discuss not only your most recent and exciting data but, but to also cast some light on seemingly tough problems and hurdles that you are struggling with in advancing your project. Get together with PhD students and PostDocs from various stem cell labs within the GSCN to share ideas, experiences, potential troubles and unanswered questions in an informal setting. We will dig deeper into your research results, especially roadblocks and problems, to discuss them from various perspectives. If more than 22 registrations are received, the participants will be selected by the organizers and informed by 30 June 2017. Participation is free of charge, a social evening and accommodation on the 13th of September will be covered by the GSCN.Organizers: Giulio Abagnale (Aachen), Nicolas Huber (Jena), Juliane Jung (Jena) and Magdalena Laugsch (Cologne) |
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© German Stem Cell Network (GSCN) e.V., 2017
Last updated 20/02/2017, Powered by Webdesigner Berlin
Last updated 20/02/2017, Powered by Webdesigner Berlin