Working groups workshops

GSCN Training „Where is my career going? Where do I want to take it?“

Date: 27 March 2026 in Berlin

Venue:
Rahel Hirsch Center (RHC)
Charité
LuisenStr. 65
10117 Berlin

One-day training!
Cost: 50 € for GSCN members, 80€ for non-members
No travel or hotel costs

➚ Register here 

This training aims to address YOUR career questions! 
Our workshop will give you orientation for your further career development during and after your PhD: Self-analysis (introspection), career options, and skill development.
So, you finally have a science degree- or will in the future. What to do with it?
Are all doors open to you or is there still a lot of work to be done?
In this course you´ll learn about:
About yourself:
Your interests, values and skills

Career options
There are many more options than you think and you will be able to change between them.
Shall I do a postdoc or not?
Skill development

Which (hidden) skills do you already have,
which can you develop during your time in academia
Skills match: What do employers want from you? How to sell yourself?

All participants receive a script of the course in PDF format for offline and future use so that they can work through the material offline as well as after the course. All videos contain a full, downloadable transcript. All eBooks on the learning platform are downloadable in pdf format.

GSCN Workshop „Computational single-cell genomics for stem cell biologists“ 2025

Date: 13 & 14 Oct. 2025 in Neuherberg / Munich

Venue:
Helmholtz Center Munich
HDR (Building 3620) (→ campus map)
Ingolstädter Landstr. 1
85764 Neuherberg

Public transport:
Bus lines 294 and 295 stop directly in front of the campus at Helmholtz-Zentrum.

You absolutely need the image from the shared website (Sara’s mail) on your mobile device and show it to the gatekeeper for quick access.

➚ Register

This workshop aims to equip stem cell biologists with a comprehensive introduction to computational single-cell genomics, focusing on data analysis
using software from the scverse ecosystem. Designed for both beginners and advanced users, the workshop will provide hands-on experience with key tools for processing and analyzing multiple single-cell data modalities, including:

● Single-cell RNA sequencing (scRNA-seq)
● Spatial transcriptomics

Audience: Stem cell biologists (PhD students, Postdocs, Research associates) working with single-cell genomics data. Participants need to bring their own laptop.

● Beginners: first steps into single-cell data, little to no coding experience. ○ Min / max number of participants: 7 / 12
● Advanced: have already had hands-on data and some coding experience, ideally in Python. ○ Min / max number of participants: 7 / 12

The workshop duration is 1.5 days, and it will provide preliminary materials, including 1h of technical troubleshooting prior to the workshop to assist participants in setting up their programming environment and resources to enable them to begin programming in Python.
Learning objectives:

● Understand the fundamental concepts of single-cell data analysis.
● Learn best practices for preprocessing, quality control, clustering, visualization, and others using tools like scanpy, squidpy.
● Gain hands-on experience with advanced analysis techniques such as trajectory inference, batch-effect correction, cell cell communication and spatial analysis.
● Develop skills to interpret single-cell data in the context of stem cell biology.

The workshop will balance theoretical principles with interactive coding sessions, ensuring that participants at all experience levels can confidently apply scverse tools to their own single-cell datasets.

Interested participants will be able to contact one of the presenters (through Zulip or Zoom) regarding any preliminary materials or issues with software installations.

Fee (just for the course, no hotel, no dinner, no travel reimbursement included): 
regular non-member  – 320 €
regular member          – 260 €
student non-member – 260 €
student member         – 210 €

Register  here


Program (Syllabus):
First day
We will have 1h of technical troubleshooting to set up the working environments from 11:00 – 12:00.

13:00 – 13.15Introduction
13:15 – 14:00Commun lecture on:
Basic pre-processing of single-cell RNA-seq data
Interpretive analysis using pydeseq2
14:00 – 15:00Coding practice and troubleshooting session
Group A (Advanced) – room: TBD
Group B (Beginners) – room: TBD
15:00 – 15:30Coffee break
15:30 – 16:15Commun lecture on:
Batch correction
Trajectory analysis
16:15 – 18:00Coding practice and troubleshooting session
Group A (Advanced) – room: TBD
Group B (Beginners) – room: TBD

Second day

09:00 – 10:00Commun lecture on:
Ligand-receptor interactions
Differential cellular abundance
10:00 – 10:30Coffee break
10:30 – 12:00Spatial data pre-processing and analysis
14:45 – 16:15*Coding practice and troubleshooting session
Group A (Advanced) – room: TBD
Group B (Beginners) – room: TBD
12:00 – 13:00Lunch
13:00 – 14:00Commun lecture on:
Introduction to spatial transcriptomics
Spatial data
14:00 – 15:00Coding practice and troubleshooting session
Group A (Advanced) – room: TBD
Group B (Beginners) – room: TBD
15:00 – 15:30Coffee break
15:30 – 16:30Commun lecture on:
Spatially aware clustering
Niche detection
16:30 – 18:00Coding practice and troubleshooting session
Group A (Advanced) – room: TBD
Group B (Beginners) – room: TBD

GSCN Workshop „Computational single-cell genomics for stem cell biologists“ 2025

Date: 7 – 9 April 2025 in Berlin

Venue:
Rahel Hirsch Center
Luisenstraße 65
10117 Berlin

➚ Register

Audience: Stem cell biologists (PhD students, Postdocs, Research associates) working with single-cell genomics data. 
Beginners (Group B): 
first steps into single-cell data, little to no coding experience
Advanced (Group A): have already had hands-on data and some coding experience, ideally in Python. 
Goal: This workshop aims to equip stem cell biologists with a comprehensive introduction to computational single-cell genomics, focusing on data analysis using software from the scverse ecosystem. Designed for both beginners and advanced users, the workshop will provide hands-on experience with key tools for processing and analyzing multiple single-cell data modalities, including:
Single-cell RNA sequencing (scRNA-seq) 
Spatial transcriptomics
Single-cell ATAC sequencing (scATAC-seq) (for advanced attendees only)

The workshop will provide preliminary materials including online consulting sessions to assist beginners set up their programming environment and resources to enable them to begin programming in Python. By the end of the workshop, participants will:

Understand the fundamental concepts of single-cell data analysis.
Learn best practices for preprocessing, quality control, clustering, visualization, and others using tools like scanpy, squidpy and muon.
​Gain hands-on experience with advanced analysis techniques such as trajectory inference, batch-effect correction, multi-omics data integration, and spatial analysis. Develop skills to interpret single-cell data in the context of stem cell biology.

The last day will give participants the opportunity to apply their new skills on either their own data or curated mini-projects with the guidance of the trainers.The workshop (syllabus below) will be preceded by optional preliminary help sessions. The help sessions are intended to encourage participants who are new to programming and wish to get a head-start. Interested participants will be able to contact one of the presenters (through Zulip or Zoom) regarding any preliminary materials or issues with software installations.

Fee (just for the course, no hotel, no dinner, no travel reimbursement included): 
regular non-member  – 320 €
regular member          – 260 €
student non-member – 260 €
student member         – 210 €

Register  here


Program (Syllabus):
Monday, 07 April 2025

09:00 – 10:00AnnData in single-cell (scverse speaker)
10:00 – 11:30i    Basic pre-processing of single-cell RNA-seq data
ii    Batch effect correction
iii    Interpretive analysis using pydeseq2
11:30 – 12:00Coding practice and troubleshooting session
12:00 – 13:00Lunch
13:00 – 14:30Group B (Beginners): Trajectory analysis in single-cell RNA-seq
Group A (Advanced): scATAC-seq preprocessing with ArchR/SCENIC
14:45 – 16:15Continued:
Group B: Trajectory analysis in single-cell RNA-seq
Group A: scATAC-seq preprocessing with ArchR/SCENIC
16:30 – 17:30Coding practice and troubleshooting session

Tuesday, 08 April 2025

09:00 – 10:00Scientific lectures
10:00 – 11:30Advanced scRNA-seq analyses:
i    Ligand-receptor interactions
ii    Differential cellular abundance 
11:30 – 12:00Coding practice and troubleshooting session
12:00 – 13:00Lunch
13:00 – 14:30Spatial data pre-processing and analysis
14:45 – 16:15Continued:
Spatial data pre-processing and analysis
16:30 – 17:30Coding practice and troubleshooting session

Wednesday, 09 April 2025

09:00 – 10:00Scientific lectures
10:00 – 11:30*Option 1: Reproduce figures from a published paper
Option 2: Get consultative feedback on your own analysis
11:30 – 12:00Short presentation from interested participants
12:00 – 13:00Fare well

* For the last day, the participants may choose to either reproduce figures from a published paper using the code/tools we discuss during the previous two days or get consultative feedback on their analysis on their own data. Please be mindful of the presenters’ time to ensure you have only consultative questions and not debugging or troubleshooting questions as that may not be feasible during the allocated time.

2024

GSCN Workshop on Computational Biology

The workshop introduced computational single cell genomics for stem cell biologists usig the programms R and Python.

„The idea of the workshop is great, and I appreciated a lot its program and the single cell analysis aspects that were discussed during that. Many thanks to Sara and her brilliant explanations, it was really enjoyable.“ (anonymous participant, online survey)

2023

GSCN workshop
New developments in disease modeling and drug discovery

Date: 16 & 17 Nov. 2023

Venue: LIFE & BRAIN, Bonn, Venusberg-Campus 1, building 76, 53127 Bonn, Germany

This two-day workshop brought together experts from stem cell-based disease modeling and drug development and address the latest developments in this rapidly expanding field.
The event featured expert talks from academia and pharma, moderated discussion rounds and short project vignettes by the workshop participants. 
Topics that have been addressed ranged from biological and infrastructural prerequisites for stem cell-based drug discovery to strategic issues such as proper placement of stem cell tools in the pharmaceutical value chain. 
We had a focused and highly interactive event on the beautiful Bonn Medical Campus!

Speaker list:

Flyer  here

Program:

Thursday, 16 November 2023

until 12:00individual arrival at LIFE & BRAIN, Bonn, Venusberg-Campus 1, building 76, 53127 Bonn, Germany
12:00 – 12:10Welcome
Daniel Besser, GSCN / BIH @ Charité & Oliver Brüstle, LIFE&BRAIN GmbH
 I. Biology: Prerequisites for high fidelity hPSC-based drug discovery
12:10 – 12:30Progress and challenges in neural disease modelling 
Oliver Brüstle, LIFE&BRAIN GmbH
12:30 – 13:00Standardization & QC: (inter) national approaches for harmonization in iPSC production 
Harald StachelscheidBIH/Charité, Berlin
13:00 – 13:30Modeling physical forces with iPSCs: Requirements for heart diseases
Karl-Ludwig LaugwitzTU Munich
13:30 – 14:00Human stem cell-derived dopaminergic neuron and microglia models for phenotypic drug discovery
Johannes WilbertzKsilink Strasbourg
14:00 – 14:45Lunch break in the LIFE&BRAIN foyer
14:45 – 15:15iPS cells as important tool to support drug development
Florian Meier, Boehringer Ingelheim
15:15 – 16:30Short statements by all participants
Selected project vignettes (5 min each, 9 presentations) 
Workshop participants
16:30 – 16:50Coffee break
 Workshop Discussion Round I
16:50 – 17:15Cellular requirements for hPSCs and derivatives
Moderators: Karl-Ludwig Laugwitz & Michael Peitz
17:15 – 17:40Process standardization, scaling  and automation
Moderators: Harald Stachelscheid & Johannes Wilbertz
17:40 – 18:05Shaping appropriate read-outs
Moderators: Florian Meier & Jutta Meyer
19:30 – 22:00Joined dinner at „S im Carré“ (included)

Friday, 17 November 2023

 II. Strategy: Efficient allocation of hPSC tools in pharmaceutical value chains
09:00 – 09:30iPSC based models: how to slot them in the drug development process?
Jan Eickhoff, LDC Dortmund
09:30 – 10:00Small molecule drug discovery using iPS-derived assays: drug repurposing vs. novel compounds
Ole Pless, Fraunhofer ITMP
10:00 – 10:30Role of iPSC-derived models in preclinical R&D at Bayer AG
Jutta Meyer & Manuel Grundmann, Bayer AG
10:30 – 11:00Advancing drug discovery through precision medicine using iPSC and transcriptomics data
Sandra Lubitz & Henrik Renner, Evotec AG, Hamburg
11:00 – 11:30Coffee break
 Workshop Discussion Round II
11:30 – 12:00Where is the right place of iPSC models in the drug development process?
Moderators: Sandra Lubitz & Ole Pless
12:00 – 12:30The academia – pharma interface: Financial incentives for early value chain contributions
Moderators: Jan Eickhoff & Karl-Ludwig Laugwitz
 Wrap Up & Quo Vadis
12:30 – 13:00Compiling the key challenges and requirements identified in the workshop
Oliver Brüstle & Jan Eickhoff
13:00 – 14:00Lunch in the LIFE&BRAIN foyer & departure

Trainer


Philipp Gramlich

Dr. Philipp Gramlich has studied and researched chemistry (>3000 citations, Google Scholar 2022) at five   universities in Germany, Australia and Scotland. He gained experience in industry, first at baseclick, a biotechnology start-up and later at Eurofins Genomics as Teamleader R&D, QC and Analytics, being responsible for up to 22 staff. Since 2016, he is fully focusing on his work as co-founder of NaturalScience.Careers. He specialises in seminars and talks about career development, leadership and presentation skills.

Contact

Stefanie Mahler
stefanie.mahler@bih-charite.de

German Stem Cell Network (GSCN)
c/o Charité Universitätsmedizin
Luisenstr. 65
10117 Berlin

Trainers


Sara Jiménez
 (on-site)
Sara Jimenez is a joint postdoc in Theis lab and Lickert lab at Helmholtz Munich, where she works with computational methods to analyze single-cell genomics data in the context of pancreas development and T1D. She has given introductory scverse workshops for single-cell RNA sequencing data analysis.
Mail: sara.jimenez@helmholtz-munich.de

Francesca Drummer will be the trainer at the workshop in Munich 2025 as replacement for Tim Treis.
Mail: Francesca.Drummer@helmholtz-munich.de


Tim Treis (on-site) – not in Munich 2025
Tim Treis is a PhD student in the lab of Fabian Theis at Helmholtz Munich, where he develops computational methods for spatial multi-omics and morphology data analysis. As a scverse core member, he helps build and maintain open-source tools that integrate single-cell and spatial omics with a particular focus on the SpatialData and Squidpy packages.
Mail: tim.treis@helmholtz-munich.de

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