With regard to a possible clinical application, the following criteria are relevant for stem cells:
➤ Reproducibility: It must be possible to multiply the stem cells in sufficient quantities in culture.
➤ Differentiability: It must be possible to stimulate them to differentiate into the required cell type in great numbers.
➤ Purity: It must be possible to obtain differentiated cells of a single cell type, not cell mixtures.
➤ Precise integration: It must be possible to transplant the cell or tissue replacement to the correct site in the body.
➤ Safety against tumor formation: It must be ensured that the transplants do not continue to grow uncontrolled or form tumors.
➤ Long-term therapeutic effectiveness: The transplants must prove their functionality in the organism and have a therapeutic effect over a longer period of time.
➤ Immunocompatibility: Cell transplants should not be rejected by the immune system of the recipient organism.
Contents of the former Stem Cell Network.NRW website
➤ Translational Research:
➤ Concept
➤ Clinical studies
➤ Further Information
➤ Discover:
➤ What are stem cells?
➤ Types of stem cells
➤ Stem cell applications
➤ Questions and challenges
➤ Ethics and legal aspects
➤ Information for patients
➤ Research approaches
➤ Explore stem cells
➤ For schools
➤ For doctors
➤ Expert referral
This information on the Stem Cell Network.NRW are also available in German → here.
Diese Informationen zum Stammzellnetzwerk.NRW stehen → hier auch auf Deutsch zur Verfügung.